2013-2014 Lunch and Learn Webinar Series

Co-Sponsored by ABC Laboratories

Organized by:  Julie Eble, Critical Path Services, Cody Howard, California Air Resources Board, Laura McConnell, Bayer CropScience

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The 2013-2014 AGRO Lunch and Learn Webinar Series is complete.  A new series will begin late fall 2014.  All rights reserved by AGRO Division.

Webinar Recordings

This webinar was presented on December 11, 2013.  Click on a title to hear a recording and view slides of the presentation.

Metabolite Identification: The Impact and Utilization of High Resolution Accurate Mass Spectrometry

Mansoor SaeedImpact of High Resolution Accurate Mass (HR/AM) on Metabolite Identification
Mansoor Saeed, Ph.D., Smithers Viscient, Senior Manager, Accurate Mass Spectrometry

High resolution accurate mass spectrometry (HRAM) plays an important role in this process, identifying metabolites and the site of metabolism. This presentation covers the merit of modern HRAM by addressing the power of mass resolution, accurate mass measurements, elemental composition determinations, and the use of data-processing techniques.

Ray SanchezAccurate Mass Analyses in Support of Chemical Research and Development
Ray Sanchez, Ph.D., Smithers Viscient, Senior Chemist, Environmental Fate and Metabolism

Many molecules in the Ag Chem arena can have the same exact mass and empirical formula but are structurally different. This can lead to false positives in screening assays, as well as difficulties during structure elucidation. Examples of how accurate mass spectrometry coupled with fragmentation analysis will be presented.

This webinar was presented on January 8th, 2014.  Click on the title to hear a recording and view slides of the presentation.

Keith SolomonArriving at the truth: Weight of evidence for assessing risks of agrochemicals
2013 Sterling B. Hendricks Memorial Lectureship Award Presentation

Professor Keith R. Solomon, University of Guelph, Ontario, Canada

Information and data on agrochemicals from studies published in the open literature are increasingly being used for assessment purposes by regulatory agencies in many jurisdictions, including North America and Europe. Because most of these studies are not conducted to the standards required of GLP studies for regulatory agencies, there is a
need to assess these studies for their quality and relevance to the regulatory endpoints being considered. Weight of Evidence (WoE) offers a consistent, objective, and transparent method for assessing these studies and including them in risk assessments. The need for WoE and a method for conducting these analyses will be presented with
the herbicide atrazine as a case-example.

This webinar was presented on February 12, 2014.  Click on the title to hear a recording and view slides of the presentation.

Soil Dissipation Guidelines and Global Implications

Eva BuddeEvaluation of Terrestrial Field Dissipation Studies in Europe – A New Guidance
Eva Budde, Project Manager Environmental Fate/Modeling, Dr. Knoell Consult GmbH, Mannheim, Germany

For registration of agrochemicals in Europe, calculation of predicted environmental concentrations is mandatory. Input for the environmental fate models used for these calculations is frequently derived from terrestrial field dissipation studies. A new guidance for evaluating these studies is currently being developed by the European Food Safety Authority (EFSA). In this presentation, an overview of the procedure for deriving degradation rates as recommended in the existing material will be given, and the scientific background as well as implications on the study design will be discussed.

Richard AllenOpportunities and Challenges of Conducting Terrestrial Field Dissipation Studies for Global Agrochemicals Registration Programs
Richard Allen, Senior Manager, Valent Technical Center, Valent U.S.A. Corporation, Dublin, California

Terrestrial field dissipation studies are almost always required for registration of agrochemicals in North America and, depending upon the results of laboratory studies, frequently required in Europe.  An OECD expert group is currently engaged in developing harmonized guidance for conduct of studies and a crosswalk for comparison of North American and European Ecoregions.  Following the ACS symposium in September, this presentation will present a perspective on the opportunities and challenges of conducting these studies to better inform environmental risk assessments as well as to satisfy the regulatory data requirements of European and North American authorities.

This webinar was presented on March 12, 2014. Click on the title to hear a recording and view slides of the presentation.

Jeanette Van Emon_croppedImmunochemistry in motion: Applications to agrochemicals
2013 Award for Innovation in Chemistry of Agriculture
Dr. Jeanette Van Emon of the U.S. Environmental Protection Agency, Las Vegas, NV, USA

The US EPA became interested in immunoassays in the 1980s and undertook methods development and evaluation studies, as well as outreach and educational activities through several avenues including the Immunochemistry Summit Meeting series. This presentation will chronicle the journey of immunoassay from biomedical to agrochemical applications.

This webinar was presented on April 16 2014. Click on the title to hear a recording and view slides of the presentation.

Dr. Lois RossiPilot project leading the way toward harmonized MRLs around the world
Lois Rossi, Director, Registration Division, Office of Pesticide Programs, US Environmental Protection Agency

US EPA has been involved over the years with multiple initiatives supporting harmonization of regulations for pesticides registration and control. Feedback will be presented from a pilot project developed in cooperation with the Joint FAO/WHO Meeting on Pesticide Residues (JMPR) for parallel review with OECD-Joint Registration Review. Sulfoxaflor is new insecticide that has applied for registration for use on multiple crops in different countries, based on a global registration package. Some details around the global joint-review and feedback from the pilot project developed with Codex process for setting MRLs will be presented.

This webinar was presented on May 14, 2014. Click on the title to hear a recording and view slides of the presentation.

Dr. Peter GreenUnexpected Issues of Air Quality Arising from Agriculture
Dr. Peter Green, University of California, Davis, Air Quality Research Center, Davis, California

Air quality in non-urban areas is usually better than in large cities.  However, contributions from agriculture can be significant and are still not fully understood. This talk will focus on the formation of ozone from sources such as pesticide solvents, animal feed, and composting. In addition, I will discuss trade-offs with other emissions such as greenhouse gases as well as groundwater impacts.