skip to Main Content

Ivermectin – broad spectrum anti-parasitic agent first approved for use

Ivermectin is part of the broader class of avermectins that are veterinary and human antiparasitic agents. Avermectins were first shown to have activity in a mouse bioassay.  The structures and activities as well as improved fermentation yields enabled commercialization of ivermectin as a veterinary drug with the first product approval in 1981. Activity against Onchocerciasis (river blindness) was demon-strated in the mid-1980s and Merck partner-ed with WHO and other organizations to donate billions of doses of ivermectin to afflicted countries from 1987 to present for onchocerciasis as well as lymphatic filariasis.
View Source

Back To Top